Biochem/physiol Actions

Reversible: no

Product does not compete with ATP.

Primary TargetMMP-2

Cell permeable: yes

General description

Potent inhibitor of MMP-2 (gelatinase A). Inhibits MMP-2 in a dose dependent manner (K_i = 1.7 µM)

A cell-permeable, potent inhibitor of MMP-2 that acts in a dose-dependent manner (K_i = 1.7 µM).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Berton, A., et. al. 2001. J. Biol. Chem.276, 20458.Emonard, H., et al. 1999. Ann. N.Y. Acad. Sci.878, 647.

Packaging

Packaged under inert gas

10 mg in Plastic ampoule

Reconstitution

Unstable in solution; reconstitute just prior to use.

Warning

Toxicity: Standard Handling (A)